Are Peptides Right for Everyone? What to Know Before Starting Peptide Therapy

Peptide therapy has become a buzzy phrase in wellness medicine, and for good reason. Peptides like BPC-157, CJC-1295 + Ipamorelin, and Sermorelin are being used to support healing, hormone balance, and recovery. We’re excited to begin offering them here at SynergenX too!

But here’s what you might not hear online: peptides aren’t for everyone. Some people can benefit tremendously, while others could risk making existing health conditions worse.

If you’re thinking about trying peptides, here’s what you need to know before you start.

What Are Peptides, Really?

Peptides are chains of amino acids, small pieces of proteins that help your body communicate, heal, and regulate hormones.

Different peptides have different functions:

• BPC-157 supports tissue repair and gut health.
• CJC-1295 + Ipamorelin encourages natural growth hormone production for recovery and metabolism.
• Sermorelin supports energy, sleep, and healthy aging by stimulating growth hormone release.

When prescribed correctly and monitored by a professional, peptide therapy can be safe and effective. But some medical conditions can make them risky.

Who Should Not Use Peptides

1. People with Active Cancer or a History of Tumors

Peptides like BPC-157 and CJC-1295 may promote tissue growth and new blood vessel formation, helpful for healing, but potentially dangerous if cancer cells are present.
Always consult a doctor or oncologist before starting any growth or regenerative peptide.

2. People with Kidney or Liver Disease

The kidneys and liver help filter and metabolize peptides. If these organs aren’t functioning well, peptides can build up or stress the system.

For example, BPC-157 has no safety data in patients with chronic kidney disease (CKD), and while it’s anti-inflammatory, it hasn’t been studied in renal-compromised populations.
If you or a loved one has stage 3 or higher kidney disease, peptides should only be used under direct nephrologist supervision, if at all.

3. People with Uncontrolled Diabetes or Blood Sugar Issues

Peptides like CJC-1295, Ipamorelin, and Sermorelin can influence insulin sensitivity and glucose regulation.
Those with uncontrolled diabetes or reactive hypoglycemia should be monitored closely or avoid these therapies altogether.

4. People with Cardiovascular or Vascular Disorders

Some peptides can affect blood flow, fluid retention, or vascular tone.
If you have heart failure, high blood pressure, or a history of blood clots, peptides should only be prescribed after cardiac clearance.

5. People with Autoimmune Conditions

Because peptides can influence immune signaling and inflammation, they can occasionally worsen autoimmune diseases such as lupus or rheumatoid arthritis.
Treatment should be personalized and closely monitored by a medical provider.

6. Pregnant or Breastfeeding Women

Peptides such as BPC-157, CJC-1295, and Sermorelin have not been studied for safety during pregnancy or breastfeeding and should be avoided.

7. Anyone Using Unregulated or Online Peptides

Online “research” peptides are not pharmaceutical grade, not sterile, and often contaminated.
At SynergenX, all peptides are:

• Compounded in certified U.S. pharmacies
• Prescribed by licensed medical providers
• Monitored for safety, dosage, and effectiveness

Who Can Benefit from Peptides

When used safely and appropriately, peptides can help:

• Support recovery from injuries or training
• Improve energy, focus, and sleep
• Promote muscle maintenance and healthy aging
• Support gut and joint health

If you’re healthy, cleared by your healthcare provider, and looking to enhance recovery or wellness, peptides can be a valuable tool, but only under medical supervision.

In Summary

Peptides can be powerful allies in health, but they’re not a one-size-fits-all solution.
If you have kidney disease, cancer, or other chronic conditions, it’s best to avoid peptides unless prescribed by a medical professional familiar with your full health history.

At SynergenX, our providers take time to evaluate your labs, medications, and goals to determine if peptide therapy is right (and safe) for you.

Ready to learn more? Schedule a free consultation today to learn if peptide therapy is a good fit for your body and health goals.

Sources

1. Sikiric, P. et al. Stable gastric pentadecapeptide BPC-157: A novel therapy for various inflammatory and healing processes. Pharmaceuticals. 2023;18(2):185. MDPI
2. Kang, E. A. et al. Potential of BPC-157 in healing and tissue regeneration. Journal of Orthopaedic Surgery & Research. 2019;14:310. JOSR
3. National Center for Biotechnology Information. Peptides in regenerative medicine: overview and safety considerations. NIH