If left untreated, hormone deficiency in men—particularly low testosterone—can contribute to or worsen several health issues. The connection between testosterone and systemic health is well documented, and low levels have been associated with the following risks:

Obesity

There is a two-way relationship between hormone deficiency and excess body fat.

• Men with Low T are more likely to accumulate abdominal fat.
• Obesity increases the risk of insulin resistance, chronic inflammation, and hormonal imbalance.

Obesity is also associated with increased risk of type 2 diabetes, heart disease, metabolic syndrome, COPD, and certain cancers.

Chronic Obstructive Pulmonary Disease (COPD)

Testosterone does not directly cause COPD. However, lower testosterone levels have been linked to reduced lung function and may worsen respiratory symptoms in men with existing pulmonary conditions. Research suggests that optimal testosterone levels may support better breathing capacity and oxygen regulation.

Type 2 Diabetes

Testosterone contributes to glucose metabolism and insulin sensitivity.
When testosterone levels are low, tissues may become less responsive to insulin, increasing the risk of type 2 diabetes.

Several studies indicate that men with low testosterone are significantly more likely to develop metabolic disorders during midlife or later.

Cardiovascular Disease

Testosterone is involved in cholesterol regulation and vascular function. Low T may contribute to:

• Elevated LDL (bad) cholesterol
• Reduced HDL (good) cholesterol
• Arterial stiffness and plaque buildup

These changes can increase the risk of heart attack, stroke, and other forms of cardiovascular disease, including coronary artery disease (CAD) and peripheral artery disease (PAD).

Cognitive Decline and Neurodegenerative Disorders

Testosterone may help support cognitive clarity, memory function, and visuospatial awareness.
Men with clinically low testosterone levels appear to have a higher risk of:

• Mild cognitive impairment (MCI)
• Alzheimer’s disease and other dementias

While research is ongoing, hormone deficiency has been proposed as a contributing factor in age-related cognitive decline.

Prostate Cancer Progression

Low testosterone is not a known cause of prostate cancer. However, in men who already have low-risk prostate cancer, testosterone deficiency may influence disease progression. Clinical evaluation and ongoing surveillance are essential in these cases.

Men with a personal or family history of prostate cancer should speak with a provider before starting any form of hormone therapy.

When to Get Tested for Low Testosterone

If you are experiencing:

• Decreased energy
• Reduced libido
• Difficulty concentrating
• Mood changes
• Weight gain or muscle loss

…it may be time to have your testosterone levels evaluated. These symptoms, along with others, may indicate underlying hormone deficiency that can be confirmed through a clinical consultation and lab testing.

The SynergenX Approach to Hormone Optimization

SynergenX provides thorough evaluation, diagnostic testing, and provider-guided hormone optimization for men experiencing symptoms of Low T. Every treatment plan includes:

• A comprehensive hormone panel, autonomic neurosystem test, and body composition analysis
• Custom-dosed testosterone therapy, if clinically appropriate
• Ongoing monitoring through regular lab work and provider check-ins
• Guidance designed to support long-term health, not short-term fixes

Schedule a Free Consultation Today

We believe early detection matters. SynergenX offers a full testosterone evaluation at all of our locations across Texas and Illinois. If you’re concerned about hormone deficiency or its long-term health risks, schedule your test today.