Causes of Low Testosterone in Men

Testosterone plays a vital role in a man’s energy, mood, focus, strength, metabolism, and sexual health. While it’s normal for testosterone levels to decrease slightly with age, clinically low testosterone, also known as Low T, can result from a number of different causes.

Age-Related Decline

Testosterone levels naturally begin to decline around age 30 and may continue to drop by about 1% per year. For some men, this change is mild. For others, it can lead to noticeable symptoms—such as fatigue, low libido, mood changes, and reduced muscle mass.

Age alone doesn’t always mean treatment is necessary, but it can be one of the causes of low testosterone.

Medical Causes of Low Testosterone

Testosterone levels begin to decline when something affects the body’s ability to produce or regulate hormones properly. Sometimes the issue starts in the testicles, where testosterone is made. In other cases, it’s related to how the brain signals the body to produce testosterone.

Common medical causes of low testosterone include:

• Injury or trauma to the testicles
• Certain cancer treatments, such as chemotherapy or radiation
• Problems with the pituitary gland (which helps regulate hormones)
• Infections or autoimmune conditions
• Genetic disorders, including Klinefelter syndrome

These causes are less common but important to identify, which is why every treatment at SynergenX starts with a detailed lab evaluation and provider review.

Lifestyle and Health Causes of Low Testosterone

Some men develop low testosterone due to everyday health and lifestyle factors, which can impact hormone balance over time. These may include:

• Obesity – Excess body fat may interfere with testosterone production
• Chronic stress – Long-term elevation of cortisol (the stress hormone) can disrupt hormone function
• Poor sleep – Sleep deprivation or untreated sleep apnea may reduce testosterone levels
• Excessive alcohol use – May impair the body’s hormone-regulating systems
• Certain medications – Including long-term use of opioids, corticosteroids, or anabolic steroids
• Chronic illness – Conditions such as type 2 diabetes, liver disease, or kidney disease are associated with Low T

These factors don’t guarantee you’ll develop Low T—but they may increase your risk.

How We Treat Low Testosterone

At SynergenX, we don’t assume based on symptoms alone. Our approach includes:

• A comprehensive hormone panel
• A full InBody composition scan
• A one-on-one consultation with a licensed provider
• A review of your symptoms, health history, and current medications

If Low T is confirmed and treatment is appropriate, your provider will create a personalized plan that may include custom-dosed testosterone therapy and regular lab monitoring to track your progress.

Schedule a Free Testosterone Test

If you’re experiencing symptoms like fatigue, low libido, brain fog, or weight changes, it may be time to evaluate your testosterone levels. Your consultation and testosterone test are free at all SynergenX locations.

📍 Clinics in Houston, Dallas–Fort Worth, San Antonio, Austin, and Chicago
📞 Call 888.219.7259 or schedule your visit online